Random inducible controlled expression (RICE) for identification of mycobacterial virulence genes
نویسندگان
چکیده
منابع مشابه
Characterization of mycobacterial virulence genes through genetic interaction mapping.
We have previously shown that approximately 5% of the genes encoded by the genome of Mycobacterium tuberculosis are specifically required for the growth or survival of this bacterium during infection. This corresponds to hundreds of genes, most of which have no identifiable function. As a unique approach to characterize these genes, we developed a method to rapidly delineate functional pathways...
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ژورنال
عنوان ژورنال: Tuberculosis
سال: 2011
ISSN: 1472-9792
DOI: 10.1016/j.tube.2011.10.013